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Burleigh® PCS-6000

Our Most Advanced, Motorized Micropositioning Technology

Micromanipulator PCS-6000

The Burleigh® PCS-6000 Piezoelectric micromanipulator system combines ease of use with ultra-precise positioning to achieve the best possible results with the highest productivity. Its long travel motors give flexibility for coarse positioning, and Piezoelectric technology provides extremely smooth, very precise movement for the final patch.

The Burleigh® PCS-6000 micromanipulator system combines fast, easy pipette changes with motorized easy-set memory positions and PC software to provide greater efficiency and experimental control.

Available in multiple configurations, the Burleigh® PCS-6000 is designed for the most demanding applications.

  • » Features & Benefits
  • » Pipette Exchange
  • » Configuration
  • » Piezo Technology
  • » Computer Control
  • » Specifications

Features

Benefits
Easy-set motorized memory positions Minimize experimental set-up times
Intuitive computer-controlled user interface software Easy to use with less training and less operator error
25mm of motorized travel Rapid coarse positioning for faster set-up
Piezoelectric technology with nanometer precision for fine positioning Finger tip commands are instantly converted into smooth predictable motion
Negligible drift for ultra-high stability Complete control of your experiment
Adjustable home positions on two rotary pivot stages Simple, fast and easy pipette exchange
Low-noise electronics and cables are fully shielded and carefully grounded Negligible interference with cell voltage recordings
2- year warranty 'Peace of mind'

Easy Pipette Exchange

Quick and easy pipette exchange is accomplished using the two rotary pivot stages each with adjustable stop mechanisms. The adjustable stop mechanisms, found in both the headstage and rotary pivot stage, consist of a brass block, a locking ring, two setscrews and a pin.

Once the set stops are adjusted to your working conditions, you can change pipettes easily and quickly to return to the field view under the microscope. To further simplify the pipette exchange procedure without losing your home position, use our Burleigh® PCS-500 Steep/Shallow Headstage Bracket with a sliding stage and repeatable stops at both ends of travel.

Configuration Options

Stage Example Stage Example

The optimum micromanipulator axis configuration for patching cultured cells is different from that used for traditional brain slice applications.

For cultured cell applications we recommend configuration C in which the micromanipulator axes are arranged orthogonally in X, Y and Z. The X and Y axes are used to position the patch pipette over the cell of interest, then the Z axis is used to move the pipette down to achieve the patch.

In traditional brain slice work, the patch pipette moves to the slice at an approach angle of approximately 20 to 30 degrees, thus the micromanipulator system axis configuration is Y (front to back of the microscope), Z and Approach.

We call this configuration T.

Longer Fine Travel

Fingertip commands allow ultimate control of pipette position - using three linear axes, each with 25mm of motorized coarse travel and a choice of 150μm or 300μm of fine Piezoelectric travel.


The Burleigh® Piezoelectric Technology Edge

The extremely precise, fast, and stable micropositioning you get with the Burleigh® PCS-6000 micromanipulator comes from our expertise in Piezoelectric technology. For patch-clamp applications, there is nothing smoother than Piezoelectric technology travel. Enjoy nanometer resolution for positioning your pipette, without the jerky motion, drift or backlash of hydraulics and stepper motors. Once in position, our Piezoelectric technology eliminates drift to ensure that you get the best possible results.

Why Piezo Technology will benefit you

Precise Computer Control
Control Panel

The Burleigh® PCS-6000 micromanipulator incorporates easy-set motorized memory positions,virtual joystick control and 3D positional readouts to minimize experimental setup time and increase productivity.


Piezo Motorized
Travel 150 μm or 300 μm 25mm nominal
Resolution < 60nm 1.6 μm minimum step size
Operator Interface Large knobs for piezo Joystick for motorized axes
Speed Directly proportional
to rate knob turns		 Continuously variable between 0.0005mm/sec and 2mm/sec
Memory speed 3.5mm/sec
Drift <1 μm per hour
Computer interface USB
Manipulator Dimensions*
* height can be adjusted		 6.5” x 5.5” x 7”
(length, width, height)
Warranty 2 years